无创呼吸机治疗慢性阻塞性肺疾病合并呼吸衰竭的效果

Effect of non-invasive ventilator in the treatment of chronic obstructive pulmonary disease complicated with respiratory failure

目的分析无创呼吸机对慢性阻塞性肺疾病合并呼吸衰竭疾病患者的治疗效果。方法选取2014年1月~2016年6月我院收治的90例慢性阻塞性肺疾病合并呼吸衰竭疾病患者作为研究对象,采用随机数字表法将患者分为研究组和对照组,每组各45例。对照组给予常规的扩张气管、吸氧、止咳、祛痰等疗法;研究组患者在对照组的基础上进行无创呼吸机疗法,观察两组患者治疗前后的氧分压(Pa O2)、呼吸频率(RR)、血氧饱和度(Sa O2)及心率(HR)变化和不良反应发生情况。结果研究组患者治疗后的HR[(93.82±10.37)次/min]低于对照组[(119.28±18.47)次/min],Sa O2[(99.04±4.87)%]高于对照组[(79.08±2.22)%],RR[(22.07±1.89)次/min]低于对照组[(29.81±1.98)次/min],Pa O2[(66.07±2.97)mm Hg]高于对照组[(50.12±2.11)mm Hg],差异均有统计学意义(P<0.05);研究组患者的不良反应发生率(13.33%)低于对照组(35.56%),差异有统计学意义(P<0.05);研究组患者的住院天数[(9.1±1.2)d]明显短于对照组[(13.2±2.1)d],住院费用[(8798.1±102.8)元]低于对照组[(9879.4±1129.2)元],再入院次数[(0.23±0.12)次]少于对照组[(1.98±0.89)次],差异均有统计学意义(P<0.05)。结论给予慢性阻塞性肺疾病合并呼吸衰竭疾病患者行无创的呼吸机疗法可以明显改善患者的临床症状,提高治疗效果,降低不良反应发生情况,值得临床上广泛推广。

Objective To analyze the therapeutic effect of non-invasive ventilator in the treatment of chronic obstructive pulmonary disease（COPD） and respiratory failure（RF）.Methods A total of 90 COPD patients complicated with RF treated in our hospital from January 2014 to June 2016 were selected as the subjects,and divided into research group and control group by random number table method,45 cases in each group.In the control group,routine treatments such as trachea dilation,oxygen uptake,cough relieving,and phlegm eliminating were used,while in the research group,on the basis of the control group,non-invasive ventilator was added.The oxygen partial pressure（Pa O2）,respiratory rate（RR）,oxygen saturation（Sa O2）,and heart rate（HR） before and after treatment,and occurrence of adverse reactions were observed in the two groups.Results HR after treatment in the research group（[93.82 ±10.37] times/min） was lower than that in the control group（[119.28±18.47] times/min）.The Sa O2 in the research group（[99.04±4.87]%） was higher than that in the control group（[79.08±2.22]%）,RR in the research group（[22.07±1.89] times/min） was lower than that in the control group（[29.81±1.98] times/min）,Pa O2 in the research group（[66.07±2.97] mm Hg） was higher than that in the control group（[50.12±2.11] mm Hg）,the differencse were statistically significant（P〈0.05）.The incidence of adverse reactions in the research group（13.33%） was much lower than that in the control group（35.56%）,the difference was statistically significant（P〈0.05）.The hospital stay（[9.1±1.2] d）,hospitalization cost（[8798.1±102.8] yuan）,and amount of re-admission（[0.23 ±0.12] times） in the research group were less than those in the control group（[13.2 ±2.1] d, [9879.4 ±1129.2] yuan,and [1.98±0.89] times）,the differences were statistically significant（P〈0.05）.Conclusion Non-invasive ventilator therapy for patients with COPD and RF can significantly improve the clinical symptoms,enhance the efficacy of treatment,and reduce the occurrence of adverse reactions,which is worthy of widespread promotion in clinic.