米非司酮与腹腔镜子宫肌瘤剔除术治疗子宫肌瘤的临床效果比较

Comparison of clinical efficacy of Mifepristone and laparoscopic myomectomy treating uterine fibroids

目的研究米非司酮与腹腔镜子宫肌瘤剔除术治疗子宫肌瘤的临床效果。方法选取2017年2~12月在我院接受治疗的子宫肌瘤患者64例,根据随机数字表法将其分为A组(米非司酮组)和B组(腹腔镜组),每组各32例。对A组进行米非司酮治疗,在腹腔镜下对B组行子宫肌瘤剔除术,比较两组的总有效率、患者的生活质量。结果A组的总有效率为78.1%,B组为93.8%,两组比较,差异有统计学意义(P<0.05)。A组的情感功能明显高于B组,差异有统计学意义(P<0.05),而躯体功能、认知功能、身体健康状况、社会功能和角色功能B组明显优于A组,差异有统计学意义(P<0.05)。结论与米非司酮比较,腹腔镜子宫肌瘤剔除术治疗子宫肌瘤的成功率较高,临床效果好。但用米非司酮进行药物治疗具有能明显改善患者预后情感的功能。

Objective To study the clinical effect of Mifepristone and laparoscopic myomectomy for uterine fibroids.Methods A total of 64 patients with uterine fibroids received treatment in our hospital from February to December2017 were selected.They were divided into group A（Mifepristone group） and group B（laparoscope group） through the random number table method,32 cases in each group.Patients in group A were treated with Mifepristone,and hysteromyomectomy was performed under laparoscope in group B patients.The total efficiency,quality of life of the two groups were observed and recorded.Results The total effective rate in group A was 78.1%,and the total effective rate was93.8% in group B,and the difference between the two groups was statistically significant（P〈0.05）.The emotional function of patients of group A was obviously higher than that of group B patients,the difference was statistically significant（P〈0.05）,whereas physical function,cognitive function,physical health,social function and role function of group B was better than that in group A of patients,patients with statistically significant difference（P〈0.05）.Conclusion Compared with mifepristone,laparoscopic myomectomy has a high success rate,and good clinical effect.However,the use of Mifepristone for drug therapy has the ability to significantly improve the patient′s prognosis.