吸入糖皮质激素联合不同药物治疗中度持续性支气管哮喘的临床疗效观察

Clinical efficacy of inhaled Glucocorticoid combined with different drugs for the treatment of moderate persistent bronchial asthma

目的探讨对中度持续性支气管哮喘患者予以不同药物联合吸入糖皮质激素治疗的效果。方法选取我院收治的中度持续支气管哮喘患者80例,随机分为常规组与研究组各40例。常规组行长效β_2受体激动剂联合吸入糖皮质激素治疗,研究组行缓释茶碱口服联合吸入糖皮质激素治疗。比较2组临床疗效及复发率。结果常规组患者的总有效率显著低于研究组(P<0.05);常规组患者的病情复发率显著高于研究组(P<0.05)。结论对中度持续性支气管哮喘患者予以缓释茶碱口服联合吸入糖皮质激素治疗,其治疗效果显著优于联合长效β_2受体激动剂,且能降低病情复发,值得临床推广。

Objective Explore the effect of different drugs combined with inhaled glucocorticoids on patients with moderate persistent bronchial asthma. Methods 80 patients with moderately persistent bronchial asthma received in our hospital were selected and divided into routine group and study group by random methods, with 40 cases in each group. The routine group was treatable with Long-acting β2 agonists combined with inhaled glucocorticoids, the strdy group was treated with sustained-release theophylline orally and inhaled glucocorticoid. Compare the improvement of the patients＇ condition after treatment with different drugs in the study group and the conventional group. Results The clinical curative effect rate of the routine group was significantly lower than that of the study group（P〈0.05）; the recurrence rate of the routine group was higher than that of the study group（P〈0.05）.Conclusion The sustained-release theophylline orally combined with inhaled glucocorticoids in patients with moderate persistent bronchial asthma has a significantly higher therapeutic effect than the combination of long-acting β2 agonists and can reduce the recurrence of the disease,it is worthy of clinical promotion.