中药鹿血晶治疗晚期乳腺癌化疗相关性贫血的临床观察

Clinical Study of Chinese Medicine Cervus Blood Granule for Chemotherapy-related Anemia in Advanced Breast Cancer

目的观察中药鹿血晶治疗化疗相关性贫血的疗效及安全性。方法将80例化疗后贫血的晚期乳腺癌患者,按照随机数字表法1∶1随机分为两组,对照组及治疗组各40例,分别给予重组人促红素注射液和鹿血晶纠正贫血。结果化疗前及化疗后7天两组红细胞和血红蛋白水平差异均无统计学意义(P>0.05),但化疗后14天治疗组红细胞及血红蛋白水平均明显高于对照组,差异有统计学意义(P<0.05)。两组均无严重不良反应,耐受性良好。结论中药鹿血晶能够更加迅速的纠正化疗相关性贫血,且安全性良好,可作为治疗化疗相关性贫血的可选药物之一。

Objective To evaluate the efficacy and safety of Chinese medicine cervus blood granule for chemotherapyrelated anemia. Methods 80 advanced breast cancer patients with chemotherapy-related anemia were randomly divided into 2 groups. In the control group,40 patients were treated by Recombinant Human Erythropoietin,In the treatment group,40 patients were treated by cervus blood granule. Results There were no significant difference between the 2 groups in Red blood cells and hemoglobin levels,neither before treatment nor 7 th day after treatment（ P 〉 0. 05）. but the levels of erythrocyte and hemoglobin in the treatment group were significantly higher than those of the control group on the 14 th days after chemotherapy. The difference was statistically significant（ P 〈 0. 05）. Neither group had severe adverse events,and both groups had good tolerance. Conclusion Cervus blood granule can improve chemotherapy-related anemia more rapidly and safety,It also can be used as one of the alternative medicines to treat chemotherapy-related anemia