调强放疗与三维适形放疗对宫颈癌的疗效分析

The Curative Effect of Radiotherapy and 3D Conformal Radiotherapy on Cervical Cancer

目的分析调强放疗与三维适形放疗对宫颈癌的疗效及并发症。方法选择宫颈癌患者100例为研究对象,将其按治疗方式不同分为各50例患者的研究组和对照组,研究组给予调强放疗,对照组给予三维适形放疗,比较两组患者的治疗总有效率、并发症发生率和1~2年的复发情况。结果研究组治疗总有效率为96.0%(48/50),与对照组92.0%(46/50)比较无差异(P>0.05);两组患者的白细胞下降、放射性膀胱炎发生率比较无差异(P>0.05),但研究组患者的消化道反应、膀胱反应和放射性肠炎的发生率明显低于对照组(P<0.05);两组患者的1年复发率和2年复发率均无统计学差异(P>0.05)。结论调强放疗与三维适形放疗均可用于宫颈癌术后的辅助治疗过程中,该两种方法的疗效和复发情况无差异,但相比于三维适形放疗,调强放疗可有效降低患者的消化道反应、膀胱反应和放射性肠炎等并发症的发生率,临床实用价值较高。

Objective To analyze the curative effect and complications of radiotherapy and 3 D conformal radiotherapy for cervical cancer. Methods 100 patients with cervical cancer were selected and divided into the study group and the control group,each with 50 patients,the study group was given IMRT,the control group was given 3 D-CRT,The total effective rate of treatment,the incidence of complications and the recurrence of 1 to 2 years were compared in the 2 groups. Results The total effective rate of treatment in the study group was 96. 0%（ 48/50） and 92. 0%（ 46/50） of the control group（ P 〉 0. 05）. In the 2 groups of patients,the incidence of white blood cells declined,radioactive cystitis had no difference（ P 〉 0. 05）,but digestive tract,bladder,and the incidence of radioactive enteritis significantly lower than the control group（ P 〈 0. 05）; There was no statistical difference between the 2 groups of patients in 1-year recurrence rate and 2-year recurrence rate（ P 〉 0. 05）. Conclusion IMRT and 3 D-CRT can be used for cerical cancer postoperative adjuvant therapy,the curative effect and recurrence have no difference of the 2 methods,but compared with 3 D-CRT,IMRT can effectively reduce the patient’s digestive tract,bladder,and radioactive enteritis,etc. clinical practical value is higher.