超声弹性成像在甲状腺结节良恶性鉴别诊断中的应用效果分析

Application of Ultrasound Elastography in Differential Diagnosis of Benign and Malignant Thyroid Nodules

目的分析超声弹性成像在甲状腺结节良恶性鉴别诊断中的应用效果。方法将在该院进行治疗的107例甲状腺结节患者临床资料回顾性分析,时间为2016年9月—2017年9月期间,经手术病理证实共存在117个甲状腺结节。分别采用超声弹性成像检查以及常规超声检查,将检查结果进行比较分析。结果手术证实的117个甲状腺结节中,超声弹性成像共检出111个,诊断准确率为94.87%,其中良性、恶性分别检出18个、93个;常规超声检查共检出甲状腺结节79个,诊断准确率为67.52%,其中良性结节占68个,恶性结节占11个;比较差异有统计学意义(P<0.05)。在甲状腺良恶性结节诊断中敏感性、特异性、阳性预测值、阴性预测值方面,超声弹性成像分别为90.00%、95.88%、81.82%、97.89%,均高于常规超声检查(χ~2=5.13、22.82、16.82、6.52,P<0.05)。结论在甲状腺结节良恶性鉴别诊断中,超声弹性成像技术的应用效果更佳,可有效区分结节的良恶性。

Objective This paper tries to analyze the application of ultrasound elastography in the differential diagnosis of benign and malignant thyroid nodules. Methods The clinical data of 107 cases of thyroid nodules treated in this hospital were retrospectively analyzed. From September 2016 to September 2017, 117 thyroid nodules were confirmed by pathology. Ultrasound elastography and conventional ultrasonography were used to compare the results. Results Of the 117 thyroid nodules confirmed by surgery, 111 were detected by ultrasound elastography. The diagnostic accuracy rate was 94.87%, of which benign and malignant were detected in 18 and 93 cases respectively. In routine ultrasound examination, 79 thyroid nodules were detected. The diagnostic accuracy rate was 67.52%, of which 68 were benign nodules and 11 were malignant nodules. The difference was statiscically significant（P〈0.05）. In the diagnosis of benign and malignant thyroid nodules, the sensitivity, specificity, positive predictive value, and negative predictive value were90.00%, 95.88%, 81.82%, and 97.89%, respectively, which were higher than those of conventional ultrasonography（χ~2=5.13, 22.82, 16.82, 6.52, P 〈0.05）. Conclusion In the differential diagnosis of benign and malignant thyroid nodules,the application of ultrasound elastography is more effective and can distinguish benign and malignant nodules.