维生素D缺乏与非骨骼疾病关系的研究进展

Research progress on relationship of vitamin D deficiency and non-bone diseases

近年来的研究发现,维生素D不仅在骨骼疾病中发挥重要作用,在非骨骼疾病中也具有非常重要的作用。基础研究证实,维生素D受体广泛分布于体内各种组织细胞;临床研究发现,补充维生素D对预防和治疗代谢综合征及心血管疾病、自身免疫性疾病以及肿瘤有重要作用。本文就维生素D缺乏与上述疾病关系的研究进展进行综述。

In recent years,much evidence has shown that vitamin D not only plays important roles in bone diseases,but also plays more vital roles in non-bone diseases. Basic studies confirmed that vitamin D receptors are extensively expressed in various cells in the body. In clinical studies,vitamin D supplementation is essential in the prevention and treatment of tumors,metabolic syndrome,cardiovascular diseases,and autoimmune diseases. In this paper,we reviewed the progress in researches on vitamin D deficiency and above-mentioned diseases.