泮托拉唑治疗消化性溃疡出血71例临床疗效分析

Analysis of Clinical Curative Effect of Pantoprazole in Treatment of 71 Cases with Peptic Ulcer Bleeding

目的分析泮托拉唑对消化性溃疡出血症的临床治疗效果。方法随机选取2016年11月—2017年10月期间在该院治疗的消化性溃疡出血症患者142例为研究对象,将所有符合标准的患者随机分为对照组和观察组,每组71例。对照组采用西咪替丁治疗,观察组采用泮托拉唑肠溶片治疗,治疗结束后对比两组患者的治疗有效率。结果经过治疗,对照组患者的总有效率为83.10%;观察组总有效率为97.18%,两组数据经统计学处理,差异有统计学意义(χ~2=3.96,P=0.047<0.05)。结论泮托拉唑可明显改善消化性溃疡出血患者的临床症状,不良反应少,对消化性溃疡出血有较好的治疗效果,具有较高的临床应用价值。

Objective To analyze the clinical effect of pantoprazole in treatment of peptic ulcer bleeding. Methods 142 cases of patients with peptic ulcer bleeding admitted and treated in our hospital from November 2016 to October 2017 were randomly selected and divided into two groups with 71 cases in each, the control group were treated with cimetidine, whiel the observation group were treated with pantoprazole enteric-Coated tablets, and the treatment effective rate was compared between the two groups at the end of treatment. Results After treatment, the total treatment effective rate in the control group and in the observation group was respectively 83.10% and 97.18%, the difference was,statistical significance（χ~2=3.96, P =0.047 0.05）. Conclusion The pantoprazole can obviously improve the clinical symptoms of patients with peptic ulcer bleeding with few adverse reactions, and it has a better treatment effect of peptic ulcer bleeding, with a higher clinical application value.