第二产程低流量吸氧对妊娠结局的影响

The effect of maternal low flow oxygen administration during the second stage of labor on pregnancy outcome

目的观察孕妇在第二产程低流量吸氧对胎儿脐动脉血pH值以及妊娠结局的影响。方法将1 100例初产妇随机分为观察组和对照组各550例,观察组在宫口开全时给予鼻导管持续低流量吸氧(2L/min),对照组给予鼻导管空气吸入,胎儿娩出后即刻检测脐动脉血pH值,并统计妊娠结局相关指标。结果观察组胎儿窘迫率、新生儿窒息率、阴道助产率、剖宫产率、产后出血率、胎儿脐动脉血pH值与对照组差异均无统计学意义(P>0.05)。结论孕妇在第二产程低流量吸氧不影响胎儿脐动脉血pH值,且对妊娠结局没有影响。

Objective To assess the effect of the use of low flow maternal oxygen during the second stage of labor on the umbilical cord artery pH and pregnancy outcome.Methods In this randomized controlled trial（RCT）, 1 100 women undergoing the second stage of labor who had no complications were randomly allocated to receive either oxygen at a flow rate of 2 L/min or sham at a flow rate of 0 L/min by the nasal cannula. Management of labor were similar in the two groups. Primary outcome was umbilical cord artery pH, and other pregnancy outcomes were recorded.Results There were no significant differences between the two groups in the fetal distress rate, neonatal asphyxia rate, instrumental vaginal delivery rate and cesarean section rate.Conclusion The use of 2 L/min maternal oxygen during the second stage of labor could not affect the umbilical cord artery pH,and could not improve the pregnancy outcome.