疝气修补术中七氟醚与异丙酚联合氯胺酮麻醉的应用效果

Application effect of sevoflurane and propofol combined with ketamine anesthesia in hernia repair

目的研究疝气修补术中七氟醚与异丙酚联合氯胺酮麻醉的应用效果。方法选取68例疝气修补术患儿,按照麻醉方法分为对照组和研究组,各34例。对照组选用氯胺酮与异丙酚联合麻醉,研究组选用氯胺酮与七氟醚联合麻醉。比较两组麻醉前后SpO_2、HR及MAP变化,手术时间、术后清醒时间、术中血氧饱和度及氯胺酮追用率。结果两组手术时间、术后清醒时间,麻醉前后的SpO_2、HR及MAP比较均无显著差异(P>0.05);研究组术中血氧饱和度<95%的占比、氯胺酮追用率显著低于对照组(P<0.05)。结论七氟醚与异丙酚联合氯胺酮麻醉方式应用于疝气修补术麻醉中均具有显著效果,但氯胺酮与七氟醚联合麻醉效果更优,可使氯胺酮追用率下降,维持术中血氧饱和度稳定,值得推广应用。

Objective To study the application effect of sevoflurane and propofol combined with ketamine anesthesia in hernia repair.Methods A total of 68 children of hernia repair were selected and divided into control group and study group according to the method of anesthesia, with 34 cases in each group. The control group was given ketamine and propofol combined anesthesia, and the study group was given ketamine and sevoflurane combined anesthesia. The changes of SpO2,HR and MAP before and after anesthesia, operation time, postoperative waking hours, intraoperative blood oxygen saturation and ketamine recovery rate between the two groups were compared.Results There were no differences in the SpO2, HR and MAP before and after anesthesia, operation time, postoperative waking hours between the two groups（P〈0.05）. The rate of intraoperative blood oxygen saturation less than 95% and ketamine recovery rate in the study group were significantly lower than those in the control group（P〈0.05）.Conclusion Sevoflurane and propofol combined with ketamine anesthesia has significant effect in hernia repair anesthesia, but the combination of ketamine and sevoflurane has better anesthetic effect,which can reduce the ketamine recovery rate and maintain the stability of intraoperative blood oxygen saturation. It is worthy of popularization and application.