血浆输注对肝硬化患者凝血功能影响分析

目的探讨血浆输入对肝硬化患者凝血功能的影响。方法选取2叭5年5月至2017年4月有血浆输注史的肝硬化患者，分析其血浆输注原因及血浆输注前后凝血功能指标的变化。结果纳入有血浆输注史的肝硬化患者174例，肝硬化患者血浆输注的主要原因为改善凝血功能。血浆输注后患者凝血功能指标中凝血酶原时间（PT）、国际标准化比值（INR）与输注前比有所下降，差异有统计学意义（t=2．49、2．08，P〈0．05）。结论本院针对肝硬化患者的血浆应用存在一定的不合理性，从凝血功能指标看，血浆输注能改善肝硬化患者凝血功能。

Objective To investigate the effect of plasma infusion on coagulation function in patients with liver cirrhosis. Methods Patients with cirrhosis who had history of plasma transfusion from May 2015 to April 2017 were selected as the study subjects.The causes of plasma transfusion and the changes of coagulation function before and after plasma infusion were analyzed. Results 174 hepatic cirrhosis patients who had history of plasma transfusion were selected, the main reason of plasma transfusion was to improve patients＇ blood coagulation in hospital. The patients＇ blood coagulation function indexs like prothrombin time （PT） and international normalized ratio （INR） decreased and the difference was statistically significant （ t=2.49, 2.08 respectively, P〈0.05 ） . Conclusion Plasma transfusion for hepatic cirrhosis patients has a certain degree of irrationality in our hospital, but from the aspect of blood coagulation function indexs, plasma transfusion improves hepatic cirrhosis patients＇ blood coagulation function.