超声对儿童孤立性左心室心肌致密化不全整体左心功能的评价

Left ventricular global functional evaluation of isolated left ventricular noncompaction in children

目的研究不同左心室收缩功能状态下孤立性左心室心肌致密化不全(iLNVC)患儿ICT、IRT、ET以及Tei指数的差异,探索iLNVC对儿童左室心功能的影响。方法纳入45例iLNVM患儿(A组:15例左心室收缩功能减低,LVEF<55%;B组:30例左心室收缩功能正常,LVEF≥55%)与正常对照组(C组:30例),检测各组左心室ICT、IRT、ET以及Tei指数间差异。结果 A组ICT较C组延长(P<0.05);A组的IRT最长,B组次之,C组最短(P<0.05);A、B、C组ET比较差异无统计学意义(P>0.05);A组的Tei指数最大,B组次之,C组最小(P<0.05)。结论iLNVC患儿出现左心室收缩功能减低前可能已存在舒张功能的异常,利用Tei指数评价左心室整体功能,有助于早期发现iLNVC患儿的左心室心功能异常。

Objective To summarize the differences of ICT,IRT,ET and Tei index in children with different left ventricular systolic function,and explore the influence of isolated left ventricular noncompaction（iLNVC）on left ventricular function in children.Methods 45 children with iLNVM were involved in the present study.The children were divided into group A（15 cases with left ventricular systolic dysfunction）,group B（30 cases with normal left ventricular systolic function）and group C（normal control group）.The difference between ET and Tei index among group A,group B and group C were analyzed.Results The ICT in group A was longer than that in group C（P〈0.05）.The IRT of group A,group B and group C were the longest,the second and the shortest（P〈0.05）.There was no significant difference in ET among 3 groups（P〉0.05）.The Tei index of group A,group B and group C were the largest,the second,and the lest（P〈0.05）.Conclusion Children with iLNVC may already have abnormal diastolic function before left ventricular systolic function reduced.Tei index to evaluate left ventricular function can detect abnormal cardiac function early in iLNVC children.