局限性肾癌行保留肾单位手术和肾癌根治手术的效果比较

Comparison of Effect of Nephron Sparing Surgery and Radical Nephrectomy for Renal Carcinoma in Localized Renal Cell Carcinoma

目的研究对肾癌患者采用局限性肾癌行保留肾单位手术和肾癌根治手术对其治疗效果。方法样本为方便选取该院2016年6月—2017年12月间收治的80例肾癌患者,随机将其分为对照组与观察组,对比等治疗指标。结果观察组患者手术时间为(2.24±1.15)h、住院时间为(6.11±1.27)d、术中出血量为(65.97±15.10)mL;对照组患者手术时间为(4.78±1.24)h、住院时间为(9.51±2.48)d、术中出血量为(112.3±35.50)mL,两组患者各项指标组间差异有统计学意义,其中观察组较为优异(t=9.499,7.718,7.595,P=0.00);观察组患者术后感染发生率为5.0%;对照组患者术后感染发生率为37.5%,组间差异有统计学意义,其中观察组较为优异(χ~2=10.124 1,P<0.05)。结论该次研究证明,对肾癌患者采用局限性肾癌行保留肾单位手术治疗有利于提高手术质量,改善患者治疗安全性,可作为临床首选治疗方法推广。

Objective To research the treatment effect of nephron sparing surgery and Radical nephrectomy for renal carcinoma in localized renal cell carcinoma. Methods 80 cases of patients with renal cancer admitted and treated in our hospital from June 2016 to December 2017 were convenient selected and randomly divided into two groups, the treatment indicators were compared between the two groups. Results The operation time, length of stay and intraoperative bleeding amount in the observation group and in the control group were respectively（2.24±1.15） h,（6.11±1.27） d,（65.97±15.10）mL and（4.78±1.24）h,（9.51±2.48）d and（112.3±35.50）mL, and the differences between the two groups were obvious（t=9.499,7.718,7.595,P=0.00）, and the incidence rate of postoperative infection in the observation group was better than that in the control group,（5.0% vs 37.5%）, and the difference was obvious（χ~2=10.124 1, P〈0.05）. Conclusion The research proves that the nephron sparing surgery for renal carcinoma in localized renal cell carcinoma is beneficial to improving the operation quality, and improving the treatment safety, and it can be promoted as the first treatment method.