乙酰半胱氨酸雾化吸入疗法治疗小儿支气管肺炎的效果研讨

Study on the effect of acetylcysteine atomization inhalation therapy on children with bronchopneumonia

目的 :探讨用乙酰半胱氨酸雾化吸入疗法治疗小儿支气管肺炎的临床效果。方法 :选择2017年10月至2018年5月期间在峨眉山市人民医院儿科接受治疗的162例支气管肺炎患儿作为研究对象。按照随机数表法将这162例患儿分为单纯用药组和雾化吸入组,每组各有81例患儿。对两组患儿均进行抗感染、止咳祛痰等常规用药治疗。在此基础上,为雾化吸入组患儿加用乙酰半胱氨酸雾化吸入疗法进行治疗。然后,比较两组患儿治疗的总有效率、各项临床症状消失的时间及不良反应的发生率。结果 :治疗后,雾化吸入组患儿治疗的总有效率高于单纯用药组患儿,其不良反应的发生率低于单纯用药组患儿,其咳嗽消失的时间、退热的时间及住院的时间均短于单纯用药组患儿,差异有统计学意义(P<0.05)。结论:在进行常规用药治疗的基础上,加用乙酰半胱氨酸雾化吸入疗法治疗小儿支气管肺炎的临床效果显著,安全性较高。

objective： to explore the clinical effect of acetylcysteine atomized inhalation in the treatment of children with bronchopneumonia. Methods： 162 children with bronchopneumonia who received treatment in the pediatric department of emeishan people＇s hospital from October 2017 to May 2018 were selected as the study subjects. According to the random number table method, the 162 children were divided into the pure medication group and the atomized inhalation group, with 81 children in each group. The two groups of children were treated with antiinfection, cough and expectoration. On this basis, the children in the atomized inhalation group were treated with acetylcysteine atomized inhalation therapy. Then, the total effective rate of treatment, the time of clinical symptom disappearance and the incidence of adverse reactions were compared between the two groups. Results： after treatment, the total effective rate of the children in the atomized inhalation group was higher than that in the pure medication group, and the incidence of adverse reactions was lower than that in the pure medication group. The duration of cough disappearance, heat reduction and hospitalization were shorter than that in the pure medication group, and the difference was statistically significant（P〈0.05）. Conclusion： the addition of acetylcysteine aerosol inhalation therapy in the treatment of children with bronchopneumonia is effective and safe.