孕前BMI和GDM与新生儿出生体质量的关系

目的探讨孕前体重指数（BMI）及孕期增重与妊娠期糖尿病（GDM）患者新生儿出生体质量的关系。方法收集2016年10月1日至2017年10月1日306例妊娠期糖尿病患者足月分娩的完整资料，采用受试者工作曲线（ROC）及回归分析孕前BMI及孕期增重与新生儿出生体质量的关系。结果妊娠期糖尿病患者孕前BMI、孕期增重与新生儿体质量存在相关性（P〈0．01）。孕前BMI预测大于胎龄儿（LGA）及巨大儿的tKOC曲线下面积分别为O．726（95％CI，0．67～0．77和0．792（95％CI，0．74～0．83），Logistic回归归分析提示孕前BMI是新生儿巨大儿的独立危险因素（OR=1．4395％CI：1．20～1．63，P〈0．01）。结论孕前BMI）K孕期增重与妊娠期糖尿病患者新生儿体质量密切相关，对LGA及巨大儿的发生有一定的预测价值。

Objective To study the associations between prepregnancy body mass index and maternal weight gain on the neonatal birth weight with gestational diabetes mellitus. Methods A tolal of 306 pregant women with gestational diabetes mellitus who received antenatal care and delivered in the People＇ s Hospital of Wenzhou from October 2016 to October 2017 were enrolled in the study. A ROC curve and regression analysis were used to demonstrate the assosiation. Results The neonatal birth weight was significantly associated with maternal BMI and maternal weight gain in women with GDM （ P〈0.01 ） . BMI predicting the LGA and fetal relevant portion of the area under the curve was 0.726 （ 95%CI：0.67～0.77 ） and 0.792 （ 95%CI： 0.74～0.83 ） . Conclusion Maternal prepregnancy BMI is significantly associated with the neonatal birth weight in women with GDM maybe has a predictive value for LGA and macrosomia.