Q开关1064nm激光治疗痤疮后并发红斑的疗效观察

目的探讨Q开关1064nm激光治疗痤疮后并发红斑的效果。方法40例痤疮后并发红宽患者随机分为治疗组（20例）与对照组（20例）。治疗组采用Q开关1064nm激光治疗，设定治疗参数（波长1064nm，光斑4mm，能量密度6．0J／cm2，频率5～7Hz）进行激光治疗，间隔1个月／次，共2次；对照组红蓝光治疗，20min／次，2次／周，共16次。治疗前后拍照并对皮损进行计数。结果治疗组总有效率为850％，明显高于对照组的20．0％，差异具有统计学意义（P〈0．05）；治疗组不良反应包括皮损处及周围皮肤少量红斑、灼热、点状出血，但在数天内可消退。结论Q开关1064nm激光治疗痤疮后并发红斑疗效确切，安全性高，无明显不良反应，是一种治疗持久性痤疮后并发红斑安全、有效的新方法。

Objective To investigate the clinnical efficacy and safety of Q-switched 1064 nm laser for the treatment of post-acne erythema. Methods A total of 40 cases of post-acne erythema were recruited and randomly divided into the treatment group （ 20 cases ） and the control group （ 20 cases ） . The treatment group received Q-switched 1064 nm laser treatment, which parameters were： 1064 nm, 4 mm spot size, 6J/ cm2, 5～7Hz. All patients were treated once a month, for 2 months. The patients in control group took red-blue light irradiation （ 20 min biw, 8 weeks ） . Pictures of erythema were taken and the numbers were recorded before and after treatment. Results The total effective rate in the treatment group was 85.0%, obviously higher than that of the control group. The difference was statistically significant （P〈0.05） . The adverse reactions included erythema, burning sensation and punctate hemorrhage on the skin and around the skin in the treatment group, but they could all disappear in several days. Conclusion Q-switched 1064 nm laser is effective and safe method for treating post-acne erythema.It is a new approach for persistent post-acne erythema.