水胶体敷料预防盐酸胺碘酮注射液所致静脉炎的临床观察

Clinical Effect of Hydrocolloidal Dressing on Preventing Phlebitis Caused by Amiodarone Infusion

目的探讨水胶体敷料预防盐酸胺碘酮注射液所致静脉炎的临床效果。方法选取2017年1-12月于四川大学华西医院心内科行外周静脉滴注盐酸胺碘酮治疗心率失常的87例患者为研究对象,于每个患者双上肢前臂同一部位各置入一个留置针,分别标记为LA(试验组)和LB(对照组),试验组在留置针穿刺针尖部位开始延血管走向粘贴水胶体敷料,对照组在相同部位粘贴其他非水胶体敷料;试验组和对照组每隔4h交替更换输注,观察两组留置针24h内不同时间段静脉炎的发生情况。结果试验组发生静脉炎10例,对照组发生静脉炎19例,两组留置针相同时间静脉炎的发生率比较,差异有统计学意义(P<0.001);两组留置针静脉炎发生程度比较,差异无统计学意义(P>0.05)。结论通过外周长时间静脉滴注盐酸胺碘酮时,应用水胶体敷料能降低静脉炎的发生率。

Objectives To investigate the clinical effect of hydrocolloidal dressing on preventing phlebitis caused by intravenous infusion of amiodarone. Methods A total of 87 arrhythmia patients who underwent peripheral infusion of anaiodarone from January 2017 to December 2017 in Cardiology Department of our hospital were enrolled in this study. A indwelling needle was placed in the same site of two forearms of each patient, which labeled as the experiment group（LA） and the control group （LB）, respectively. The hydrocolloid dressing was pasted at the injection points along with the blood vessel in the LA group, whereas other non hydrocolloid dressings were applied in the LB group. LA and LB group were alternately subjected to amiodarone intravenous infusion every 4 hours. The incidence of phlebitis at different time points within 24 h was observed in the two groups. Results Ten cases of phlebitis were observed in the experiment group and 19 cases of phlebitis in the control group （P〈0. 001）. There was a statistically significant difference in the incidence of phlebitis at the same time points between the two groups. No statistically significant difference in severity of phlebitis at the injection points was found between the two groups（P=0.07）. Conclusion The application of hydrocolloid dressing reduces the incidence of phlebitis induced by long term intravenous infusion of anaiodarone.