顽固性口腔黏膜溃疡复发因素的Logistics回归分析

Logistics Regression Analysis of Causes of Recurrence of Intractable Oral Ulcer

目的探讨顽固性口腔黏膜复发因素,对其进行Logistics回归分析,并制定针对性预防措施。方法回顾性分析我院收治的526例顽固性口腔黏膜溃疡患者临床资料,统计复发率,采用SPSS18.0软件对影响复发的相关因素进行单因素和多因素分析,综合分析结果并制定预防措施。结果本研究入选的526例患者中,复发117例,复发率为22.24%。单因素分析结果显示:年龄、是否抽烟、是否使用药物牙膏、刷牙方式、刷毛硬度、每天刷牙次数、有无消化系统慢性病、饮食类型、心理因素、食物入口温度是顽固性口腔黏膜溃疡复发的危险因素(P<0.05);多因素分析结果显示:按照危险程度依次为有消化系统慢性病(OR=7.964)、食物入口温度偏烫(OR=7.538)、每天刷牙次数≤1次(OR=7.113)、心理因素异常(OR=6.549)、刷牙方式粗暴(OR=5.987)、刷毛中硬度(OR=4.685)、饮食偏荤(OR=4.112)、使用药物牙膏(OR=3.967)、抽烟(OR=3.281)、年龄≥60岁(OR=2.643)。结论年龄、刷牙方式、饮食类型等均是影响顽固性口腔黏膜溃疡复发的危险因素,临床应根据患者具体情况制定针对性预防措施。

Objective To explore the factors leading to the recurrence of intractable oral ulcer and propose targeted meas-ures of prevention. Methods The clincal data of 526 patients with intractable oral ulcer treated in our hospital was analyzed retro-spectively to calculate the rate of recurrence. SPSS18. 0 software was used to analyze the related factors that led to the recurrence using univariate factor analysis and multivariate Logistic regression analysis. Targeted countermeasures were proposed according to the result of comprehensive analysis. Results Among the 526 patients enrolled in this study, there were 117 cases of recurrence, accounting for 22. 24％. Univariate factor analysis showed that the risk factors for the recurrence of intractable oral ulcer included age, smoking, use of medicinal toothpaste, ways of tooth-brushing, brush hardness, times of daily brushing, chronic digestive disease, diet, psychological factors, and food intake temperature （P〈0. 05）. Multivariate analysis showed that chronic digestive diseases were the dominating cause of recurrence of intractable oral ulcer （OR=7. 964）, followed by intake of hot food（OR=7. 538）, daily brushing times less than or equal to once（OR=7. 113）, abnormal psychological factors （OR=6. 549）, rough brushing （OR=5.987）, hard brush （OR=4. 685）, fatty food （OR=4. 112）, use of medicinal toothpaste （OR=3. 967）, smoking （OR=3. 281）, and age above 60 （OR=2. 643）. Conclusion Age, ways of brushing and diet are risk factors for the re-currence of intractable oral ulcer. Targeted and individualized preventive measures should be taken.