单中心经腔镜碎石上尿路结石成分分析(附542例报告)

Composition analysis of upper urinary tract stones in 542 patients treated with endoscopic lithotripsy from a single center

目的分析经中南大学湘雅二医院腔镜碎石治疗的上尿路结石患者的分布特点和结石成分的构成。方法回顾性分析2012年3月-2018年3月在该院经腔镜碎石治疗的542例上尿路结石成分红外光谱分析结果,并结合相应患者的资料进行分析。结果 542例患者男女比例为1.27∶1,高发年龄段为40~59岁,占总数的62.9%。结石构成以混合型结石为主(65.5%),各种成分结石检出率分别为草酸钙(87.5%)、碳酸磷灰石(56.3%)、磷酸铵镁(18.6%)、尿酸(12.5%),含钙结石占总数的91.1%,其中含草酸钙结石和尿酸结石患者男性比例明显高于女性。结论该组泌尿系结石成分以混合型为主,含草酸钙、碳酸磷灰石较多见,含尿酸和草酸钙结石患者中男性明显多于女性。

Objective To study the characteristics of upper urinary tract calculus from the patients treated with endoscopic lithoprisy and report the composition of stones, age and gender distribution. Methods The results of 542 samples of upper urinary tract stone composition by infrared spectrophotometer and the data relating to the patients treated by endoscopic lithotripsy from Mar, 2012 to Mar, 2018 were collected and analyzed with relevant clinical data. Results The overall gender ratio（male/female） was 1.27 ∶ 1 and the majority of these patients were aged between 40 and 59 years old（62.9%）. Among 542 samples the mixed calculi is 65.5%. The top four highest rates of components detected were calcium oxalate（87.5%）, carbonate apatite（56.3%）, struvite（18.6%） and uric acid（12.5%）, respectively, calcium stones accounted for 91.1%. The proportion of men with calcium oxalate and uric acid stone was significantly higher than that of women. Conclusions Most stones in this group were of mixed composition. Calcium oxalate and calcium carbonate apatite stones account for the most. Men were significantly more likely than women to have uric acid and calcium oxalate stones.