CA199、CA125和HE4在卵巢良性肿瘤鉴别诊断研究进展

Research progress of CA199,CA125 and HE4 in differential diagnosis of benign ovarian tumors

卵巢肿瘤对广大女性身体健康构成了重大安全威胁。目前医学影像学、细胞学及肿瘤标志物等检查是临床上较常用的针对卵巢肿瘤的诊断方法,其中影像学检查较为常见,但其存在分辨率较低、对微小病灶的诊断效果不理想等缺点。而目前肿瘤标志物检测在临床诊断卵巢肿瘤中较广泛,被认为是卵巢肿瘤诊断及评估预后的重要参考指标,肿瘤标志物的出现为卵巢肿瘤的早期诊断与鉴别诊断提供了一个新的研究方向。本文对CA199、CA125和HE4在卵巢良性肿瘤中的诊断与鉴别诊断进行综述。

Ovarian tumors pose a major security threat to the health of women. Medical imaging,cytology and tumor markers are commonly used in the diagnosis of ovarian tumors. And the imaging examination is more common,but its resolution is low,and the diagnostic effect of small lesions is not ideal. Currently tumor markers are widely used in clinical diagnosis of ovarian tumors. It is considered as an important reference index for the diagnosis and prognosis of ovarian tumors. The appearance of tumor markers provides a new research direction for early diagnosis and differential diagnosis of ovarian tumors. The diagnosis and differential diagnosis of CA199,CA125 and HE4 in benign ovarian tumors are reviewed in this paper.