多索茶碱联合布地奈德治疗支气管哮喘的临床疗效探析

Therapeutic Effect of Doxofylline Combined with Budesonide on Bronchial Asthma

目的探讨分析多索茶碱联合布地奈德治疗支气管哮喘的临床疗效。方法方便选取2013年1月—2015年12月在该院收治的支气管哮喘住院患者78例,随机分成两组,对对照组、研究组患者分别应用常规氨茶碱和多索茶碱联合布地奈德进行治疗,两组疗程均为2周,对比两组患者治疗效果。结果患者治疗结果方面,研究组治疗效果有效率为82.1%,对照组治疗效果为56.4%,研究组治疗效果明显优于对照组(χ~2=6.363,P<0.05)。治疗前两组患者的肺功能差异无统计学意义(t=1.254,2.214,1.264,1.057,P>0.05)。结论对支气管哮喘患者进行多索茶碱联合布地奈德治疗效果比茶碱或氨茶碱比较起效快,有效改善患者的呼吸功能,减少患者的临床症状,依从性高且不良反应少,安全性高,具有临床应用价值,值得进一步推广。

Objective This paper tries to explore the clinical efficacy of doxorine combined with budesonide in the treatment of bronchial asthma. Methods 78 patients with bronchial asthma admitted to the hospital from January 2013 to December 2015 were convenient selected and randomly divided into two groups. Patients in the control group and study group were treated with conventional aminophylline and doxofylline combined with budesonide treatment, two courses of treatment were two weeks, the treatment effect of the two groups of patients were compared. Results In terms of patient outcomes, the effective rate of the treatment group was 82.1% in the study group and 56.4% in the control group. The treatment effect of the study group was significantly better than that of the control group（χ~2=6.363, P〈0.05）. There was no significant difference in lung function between the two groups before treatment（t=1.254, 2.214, 1.264, 1.057, P〉0.05）. Conclusion The effect of doxofylline combined with budesonide on bronchial asthma patients is faster than that of theophylline or aminophylline, which can effectively improve the patient＇s respiratory function, reduce the patient＇s clinical symptoms, high compliance and less adverse reactions, high safety, with clinical application value, worth further promotion.