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卵巢恶性Brenner瘤一例报告并文献复习 被引量:3

Malignant Tumor of Brenner:A Case Report and the Literature Review
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摘要 目的:探讨卵巢恶性Brenner瘤(malignant Brenner tumor,MBT)的临床诊断及治疗进展,分析其临床特点,加强对卵巢恶性Brenner瘤的认识。方法:对2017年9月吉林大学第二医院收治的1例卵巢恶性Brenner瘤进行临床分析并复习相关文献,总结目前国内外诊断及治疗的进展。结果:患者经手术组织病理学及免疫组化标记确诊,术前并无特异的临床表现,免疫组化显示锌脂结构转录因子(GATA3)阳性,细胞角蛋白7(CK7)阳性,特殊的是P53与P63均表达阳性。结论:该类疾病临床表现及影像学表现缺乏特异性,诊断依靠组织病理学及免疫组化标记物,需注意与移行细胞癌相鉴别,手术切除是主要的治疗方法,标准化疗方案是卡铂加紫杉醇。 Objective:To investigate the clinical diagnosis and treatment progress of malignant Brenner tumor(MBT),analyze its clinical characteristics, and strengthen the understandings of malignant ovarian Brenner tumor. Methods:A case of malignant Brenner tumor at the Second Hospital of Jilin University in September 2017, were analyzed, and the related literatures were reviewed. The progress of diagnosis and treatment was summarized. Results:The patients were confirmed by surgical histopathology and immunohistochemical markers. There was no specific clinical manifestation. Immunohistochemistry was positive for GATA3(+) and CK7, especially for P53 and P63. Conclusions:The clinical manifestations and imaging manifestations of this disease are unspecific. The diagnosis is based on histopathological and immunohistochemical markers. It is also necessary to distinguish from transitional cell carcinoma. Surgical resection is the main treatment. The standard chemotherapy is carboplatin plus paclitaxel.
作者 毕玉晰 李洋洋 蒋杰 向梅 BI Yu-xi;LI Yang-yang;JIANG Jie;XIANG Mei(Department of Obstetrics and Gynecology,The Second Hospital of Jilin University,Changchun 130041,China)
出处 《国际妇产科学杂志》 CAS 2018年第4期373-376,共4页 Journal of International Obstetrics and Gynecology
关键词 BRENNER瘤 卵巢肿瘤 诊断 鉴别 病例报告 Brenner tumor Ovarian neoplasms Diagnosis differential Case reports
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