甲状腺结节内钙化灶的超声特征分析

Analysis of sonographyic features of calcified nodules of thyroid nodules

目的探讨不同分型钙化灶在甲状腺结节超声诊断中的应用价值。方法选取2013年1月至2017年2月上海市徐汇区大华医院超声影像科收治的96例患者105个钙化的甲状腺结节为研究对象,予超声检查对钙化分型,结合细针抽吸活检、手术病理,分析良、恶性甲状腺结节钙化特点。结果 105例结节病理:良性44例,恶性61例;微钙化对于恶性结节诊断,差异有统计学意义(P<0.05),粗钙化对于良性结节诊断,差异有统计学意义(P<0.05)。微钙化与粗钙化并存、周边弧形钙化不连续型结节对于恶性结节的阳性预测值较高,分别为73.3%、66.7%;周边弧形钙化连续型结节对于良性结节的阳性预测值较高,为88.9%。结论超声检查甲状腺结节内不同类型钙化灶,对诊断甲状腺良恶性肿瘤效果明显。

Objective To explore the diagnostic value of different types of calcification in the sonographic diagnosis of thyroid nodules. Methods One hundred and five cases of calcified thyroid nodules were selected for the study, and were detected by ultra sonography for calcification classification. With the help of fine needle aspiration biopsy and surgical pathology, the calcification features of benign and malignant thyroid nodules were analyzed. Results Pathological detection indicated that there were 44 benign cases and 61 malignant cases in the 105 cases of thyroid nodules. In the diagnosis of malignant nodules, microcalcification seemed to have statistical significance （ P 〈 0.05 ）, while in the diagnosis of benign nodules coarse calcification showed statistical significance （ P 〈 0.05 ）. In the diagnosis of malignant nodules, the presence of micro and coarse calcification, as well as discontinuous peripheral calcified nodules, all had high positive predictive rates, which were respectively 73.3% and 66.7%. However, for the diagnosis of benign nodules, continu ous peripheral calcified nodules had a higher positive predictive rate （ 88.9% ）. Conclusion Different types of thyroid nodule calcifica tion foci by ultrasonography could be used for the diagnosis of benign and malignant tumors.