甲状腺结节病理性质的超声相关影响因素及对良恶性的鉴别诊断价值比较

The related influencing factors of ultrasonography of pathological characteristics of thyroid nodules and the differential diagnostic value between benign and malignant thyroid nodules

目的探讨甲状腺结节病理性质的超声相关影响因素比较其对良恶性的鉴别诊断价值。方法选取90例收治的甲状腺结节患者,所有患者均行超声检查及弹性成像检查,分析对比超声各相关影响因素在甲状腺结节病理性质上的鉴别价值。结果结节性甲状腺肿及甲状腺腺瘤的超声弹性成像评分均等于2分,而甲状腺乳头状癌的超声弹性评分为4分。单因素分析显示,结节性质、年龄、回声性质、形态、边界、弹性评分、纵横比、有无微钙化与甲状腺结节病理性质相关(P<0.05)。多因素分析显示,弹性评分≥3级、形态不规则、年龄≥45岁、有微钙化、结节性质为实性为甲状腺结节病理性质为恶性的危险因素(P<0.05),其中弹性评分的OR值最高。结论弹性评分≥3级、形态不规则、年龄≥45岁、有微钙化、结节性质为实性为甲状腺结节病理性质为恶性的危险因素,弹性评分≥3级的危险度最高,对甲状腺结节良恶性的鉴别价值高。

Objective To investigate the related influencing factors of ultrasonography of pathological characteristics of thyroid nodules and the differential diagnostic value between benign and malignant of thyroid nodules. Methods A total of90 patients with thyroid nodules who were admitted and treated in our hospital were examined by ultrasonography and elastography. The differential diagnostic value of related influencing factors in the pathological characteristics of thyroid nodules was compared and analyzed. Results The ultrasound elastography scores of nodular goiter and thyroid adenoma were all 2 points,however the ultrasound elastography scores of papillary thyroid carcinoma were 4 points. Single factor analysis showed that the character of nodules, age, echo character, morphous, boundary, the scores of elasticity, aspect ratio,microcalcification situation of thyroid nodules were correlated with the pathological characteristics of thyroid nodules（P 0. 05）. Multivariate analysis showed that the ultrasound elastography scores ≥ 3 points,irregular shape,age ≥ 45 years,nodules with microcalcification,solid thyroid nodules were the risk factors of malignant thyroid nodules（P 0. 05）,in which the OR value of elasticity score was the highest. Conclusion The risk factors of malignant thyroid nodules are the elasticity scores ≥3 points,irregular shape,age ≥ 45 years,nodules with microcalcification,solid thyroid nodules. The elasticity scores ≥3 points has the highest differential diagnostic value between benign and malignant thyroid nodules.