社区2型糖尿病患者药学干预效果评价

Effects of pharmacy intervention on community patients with type 2 diabetes

目的评价社区2型糖尿病患者药学干预的效果。方法从杭州市富阳区3个社区各随机选取100例2型糖尿病患者,以社区为单位分为空白对照组、常规药学随访组和药学干预组,比较三组患者干预前后的糖尿病相关药学知识知晓水平、不合理用药行为、空腹血糖和糖化血红蛋白达标率,评价干预效果。结果干预前后,空白对照组糖尿病相关药学知识知晓水平、不合理用药行为、空腹血糖和糖化血红蛋白达标率均变化不大;常规药学随访组熟悉和掌握糖尿病相关药学知识的患者比例从7.00%提升至8.00%,不合理用药行为从110例次下降至78例次,空腹血糖和糖化血红蛋白达标率分别升高13.00%和14.00%;药学干预组熟悉和掌握糖尿病相关药学知识的患者比例从7.00%提升至38.00%,不合理用药行为从119例次下降至10例次,空腹血糖和糖化血红蛋白达标率分别升高21.00%和28.00%。药学干预组患者干预后糖尿病相关药学知识知晓水平的提升幅度、不合理用药行为减少幅度、空腹血糖和糖化血红蛋白达标率升高幅度均大于空白对照组和常规药学随访组(P<0.05)。结论药学干预对提高2型糖尿病患者的药学知识水平、改善不合理用药行为和控制血糖效果明显。

Objective To evaluate the effect of the pharmacy intervention in community patients with type 2 diabetes.Methods Three communities in Fuyang were randomly divided into blank-control group,ordinary pharmacy follow-up group and pharmacy intervention group. We randomly selected 100 patients with type 2 diabetes from each community as intervention subjects. The level of knowledge of diabetes medicines,the prevalence of irrational drug use,the control rate of fasting blood glucose（FBG） and glycated hemoglobin（Hb A1 c）before and after the intervention were compared in order to evaluate the effects. Results The level of knowledge of diabetes medicines,the prevalence of irrational drug use,the control rate of FBG and Hb A1 c before and after the intervention in blank-control group showed no significant difference. In the ordinary pharmacy follow-up group,the ratio of patients knowing the knowledge of diabetes medicines increased from 7.00%to 8.00%,and the case of irrational drug use decrease from 110 to 78,and the control rate of FBG and Hb A1 c increased by13.00% and 14.00%, respectively. In the pharmacy intervention group, the ratio of patients knowing the knowledge of diabetes medicines increased from 7.00% to 38.00%,and the case of irrational drug use decrease from 119 to 10, and the control rate of FBG and Hb A1 c increased by 21.00% and 28.00%, respectively. The change of those three field in the pharmacy intervention group were all significantly larger than the ordinary pharmacy follow-up group and the blank-control group（P0.05）. Conclusion Pharmacy intervention could effectively improve the level of knowledge of diabetes medicines,and the irrational drug use,and blood glucose metabolism.