颅内血肿微创清除术联合亚低温治疗重症高血压脑出血患者的临床疗效

Clinical efficacy of minimally invasive removal of intracranial hematoma combined with mild hypothermia in the treatment of patients with severe hypertensive intracerebral hemorrhage

目的探讨颅内血肿微创清除术联合亚低温治疗对重症高血压脑出血患者的临床疗效。方法选取102例重症高血压脑出血患者,随机分为对照组(n=51)和观察组(n=51)。对照组行颅内血肿微创清除术治疗,观察组在对照组的基础上加用亚低温治疗。比较2组患者临床疗效、并发症发生率及生活质量。结果 2组患者治疗后总有效率比较,差异有统计学意义(P<0.05)。治疗前,2组患者日常生活能力评定指数(BI)、格拉斯哥昏迷评分(GCS)及美国国立卫生研究院卒中量表(NIHSS)评分相比均无显著差异(P>0.05);治疗后,2组BI指数、GCS评分和NIHSS评分比较,差异有统计学意义(P<0.05);2组患者并发症发生率相比无显著差异(P>0.05)。结论重症高血压脑出血患者采用颅内血肿微创清除术联合亚低温治疗可以有效改善临床症状,提高临床疗效。

Objective To explore the clinical efficacy of minimally invasive removal of intracranial hematoma combined with mild hypothermia in treatment of patients with severe hypertensive intracerebral hemorrhage. Methods A total of 102 patients with severe hypertensive intracerebral hemorrhage were selected and randomly divided into control group （ n =51） and observation group （ n =51） . The patients in the control group were treated with minimally invasive removal of intracranial hematoma, while the patients in the observation group were treated with mild hypothermia on the basis of the control group. The clinical efficacy, incidence rate of complications and quality of life before and after treatment were compared between the two groups. Results The total effective rate showed significant difference between observation group and control group （ P 〈0.05）. Before treatment, there were no significant differences in the BI index, score of Glasgow Coma Scale （GCS）, and score of National Institutes of Health Stroke Scale （NIHSS） between two groups （ P 〉0.05）. After treatment, there were significant differences in BI index, GCS score and NIHSS score between two groups （ P 〈0.05）. The incidence rate of complications showed no significant difference between two groups （ P 〉0.05）. Conclusion The minimally invasive removal of intracranial hematoma combined with mild hypothermia can improve the clinical symptoms and increase therapeutic efficiency in patients with severe hypertensive intracerebral hemorrhage.