外泌体在防治皮肤疾病中的应用进展

Progress of exosomes on the prevention and treatment of skin diseases

外泌体是一类由细胞分泌的直径在40~100 nm之间的细胞外小泡,作为细胞间的信息传递者,具有靶向调节细胞增殖、装载药物、生物标志物等功能。研究表明外泌体参与皮肤的生理和病理过程,能有效防治多种皮肤疾病,本文就外泌体及其在防治皮肤疾病中的应用研究进展进行综述。

Exosomes are a type of extracellular vesicles with a diameter of 40-100 nm secreted by a variety of cells.As information transmitters between cells,they have the functions of targeting and regulating cell proliferation,drug loading and bio-marker.Moreover,studies have shown that exosomes participate in the physiological and pathological processes of the skin,prevent and treat various skin diseases effectively. This article reviews the recent progress of exosomes and their application in the prevention and treatment of skin diseases.