AB-8大孔树脂对艾草黄酮动态吸附工艺的研究

Study on Dynamic Adsorption Process of Artemisia argyi Flavonoids by AB-8 Macroporous Resin

为优化AB-8大孔树脂对艾草黄酮动态吸附工艺,通过单因素试验,考察上柱液浓度、流速、pH值等对AB-8大孔树脂对艾草黄酮吸附率的影响,在此基础上,利用Box-Behnken试验设计进行试验,采用反向传播(back propagation,BP)神经网络结合遗传算法对AB-8大孔树脂对艾草黄酮动态吸附工艺进行优化。结果表明:AB-8大孔树脂对艾草黄酮动态吸附的最优工艺为,上柱液浓度1.2 mg/mL,流速0.4 mL/min,pH 4.68。在此条件下,艾草黄酮吸附率可达90.28%。研究结果可为艾草黄酮进一步的生理活性研究奠定基础。

To optimize the dynamic adsorption process of ArtemJsJa argyJ flavonoJds by AB-8 macroporous resin. Single factor tests were done to study column liquid concentration, flow velocity and pH on the effect of adsorption rate of Artemisia argyi flavonoids by AB-8 macroporous resin. Box-Behnken experiment design was used to arrange the tests, BP neural network combined with genetic algorithm were used to optimize the dynamic adsorption process of Artemisia argyi flavonoids by AB-8 macroporous resin. The results showed that the optimum adsorption process of Artemisia argyi flavonoids using AB-8 macroporous resin are such as follows： column liquid concentration 1.2 mg/mL, flow velocity 0.4 mLJmin, pH 4.68. The adsorption rate could reach 90.28 % under these conditions. The results could lay a foundation for further studies on physiological activity of Artemisia argyi flavonoid.