结直肠癌患者口服化疗药依从性及相关问题研究

Research on Oral Chemotherapy Drug Compliance and Related Problems in Patients with Colorectal Cancer

目的调查结直肠癌患者口服化疗药物依从性与自我感受负担及自我效能相关性。方法本研究为前瞻性纵向研究,采用便利抽样法,于2015年2月至2017年7月,用自行设计的一般资料调查问卷、Morisky药物依从性量表,自我感受负担量表,健康促进策略量表,对129例结直肠口服化疗患者进行调查。结果患者早、中、末期化疗口服化疗药物依从性得分为6.90±1.02、6.51±1.34、6.37±1.1,自我感受负担得分为32.81±6.37、35.81±6.37、32.98±6.25,自我效能得分为81.05±26.65、81.16±26.84、81.97±27.30。不同时期口服化疗药依从性与自我感受负担呈负相关,与自我效能呈正相关关系。结论医务人员应更加关注患者中、末期化疗口服化疗药的依从性,加强健康教育及心理疏导,减轻患者心理负担,提高患者自我效能,以增强康复信心,从而提高其依从性。

Objective To investigate the correlation between oral chemotherapy drug compliance and self-perceived burden and self-efficacy in patients with colorectal cancer. Method This study was a prospective longitudinal study using a convenience sampling method. From Februa±3z 2015 to July 2017, 129 coloreetal cancer patients undergoing oral chemotherapy were investigated with a self-designed general information questionnaire, Morisky Drug Compliance Scale, Self-Perceived Burden Scale, and Strategies Used by People to Promote Health. Results At early, middle and late stage of oral chemotherapy, the compliance scores were 6.90±1.02, 6.51±1.34, and 6.37±1.1, respectively. The self-perceived burden scores were 32.81±6.37, 35.81±6.37, and 32.98±6.25, and the self-efficacy semis were 81.05±26.65, 81.16±26.84, 81.97±27.30, respectively for the three stages. Conclusion Medical staff should pay more attention to the compliance of patients with oral chemotherapy drugs at middle and late stage, strengthen health education and psychological counseling, reduce tile psychological burden on patients, and improve patients＂ self-efficacy in order to enhance their confidence in rehabilitation, and thus improve their compliance.