深圳地区235例胚胎停育常见相关因素分析

Analysis of the common related factors in embryo damage

目的:探讨导致胚胎停育发生的常见因素,为减少胚胎停育的发生及科学干预提供依据。方法:对深圳地区235例有胚胎停育史妇女进行不良生活习惯咨询,并对其进行妇科检查、子宫附件超声检查、感染因素检查、内分泌激素水平检查、ABO血型及血清抗体滴度水平检测,同时进行夫妻双方染色体核型、丈夫精液分析检查。结果:染色体异常68例(28.9%),感染因素63例(26.8%),ABO血型不合15例(6.4%),内分泌因素13例(5.5%),其他因素15例(6.4%),原因不明61例(26.0%)。结论:在发生胚胎停育的患者中,与其发生相关的因素主要为染色体异常和感染因素,如针对部分病因进行积极处理,可减少胚胎停育的发生及科学干预。

Objective To investigate the common related factors of embryonic damage,in order to provide the basis for the reduction of the occurrence and scientific intervention of embryonic damage. Method 235 cases of embryonic damage pregnant women were included,the bad living habits,gynecological examination,uterine annex ultrasound,infection factors,endocrine hormone levels,the husband and wife of chromosome karyotype,ABO blood type and serum antibody titers of these patients were consulted or checked. Results Chromosome abnormalities in 68 cases（ 28. 9%）,infection in 63 cases（ 26. 8%）,ABO blood group incompatibility in 15 cases（ 6. 4%）,endocrine factors in 13 cases（ 5. 5%）,other factors in 15 cases（ 6. 4%）,61 cases（ 26. 0%） of unknown reasons. Conclusion In the case of embryonic damage,the majority of the relevant factors can bedetected,mainly for chromosome abnormalities and infection factors. To deal with the cause of the disease,it can reduce the occurrence of embryonic development.