分娩镇痛中母体细胞因子变化的研究进展

Research progress on maternal cytokine changes during labor analgesia

疼痛可引起母体一系列应激反应及细胞因子的改变,并且对母儿造成影响。目前有研究认为,分娩过程中实施分娩镇痛可影响母体细胞因子水平,并改善母婴结局。该文就围生期细胞因子的特点、分娩疼痛的产生机制、实施分娩镇痛前后母体细胞因子的变化及意义进行综述。

Pain can not only cause a series of stress responses and cytokine changes in the mother,but also affect both the mother and infant. Current studies suggest that the use of labor analgesia can affect the maternal cytokine levels and improve maternal and fetal outcomes. In this article,the characteristics of cytokine levels during perinatal period,the mechanism of labor pain,and the changes and significance of maternal cytokine levels before and after labor analgesia were summarized.