超声引导下乳腺微小病变活检应用于乳腺癌早期诊断

Application of Ultrasound-guided Breast Microscopic Lesion Biopsy in the Early Diagnosis of Breast Cancer

目的探究超声引导下乳腺微小病变活检对乳腺癌早期诊断的临床价值.方法选取2015年6月至2017年6月于南京医科大学附属无锡妇幼保健院诊治的乳房发现微小病变的患者120例,均行超声检查、超声引导下穿刺活检以及手术切除治疗,比较2种超声诊断方式的敏感率、特异率和准确率,并对比不同超声征象与乳腺癌早期诊断的相关性.结果超声引导下穿刺活检的敏感率、特异率和准确率明显高于超声检查,差异具有统计学意义(P<0.05);边缘毛糙、低回声不均匀以及血流显示等超声征象与乳腺癌诊断具有更强的相关性,差异具有统计学意义(P<0.05).结论超声引导下乳腺微小病变活检是一种安全性较高且较为准确的乳腺癌早期诊断方式,值得临床应用.

Objective To explore the clinical value of ultrasound-guided breast microscopic lesion biopsy in the early diagnosis of breast cancer.Me thods One hundred and twenty women with breast microscopic lesion from June 2016 to June 2017 were recruited. Ultrasonic examination and ultrasound-guided core needle biopsy and operation were performed to observe the sensitivity, specificity and accuracy of the two ultrasound diagnostic methods and to compare the correlation between different ultrasonic signs and the early diagnosis of breast cancer.Re s ults The sensitivity,specificity and accuracy of ultrasound-guided core needle biopsy was significantly better than those of ultrasonic examination（P〈0.05）. Significant correlations between the early diagnosis of breast cancer and the ultrasonic signs of rough edge, hypoechoic inhomogeneity and blood flown were found（P〈0.05）.Conclus ion The ultrasound-guided breast microscopic lesion biopsy is a safe and accurate method to diagnose early breast cancer,and it is worthy of clinical application.