丹参、血必净辅助抗生素治疗胆囊炎的临床研究

Clinical study of Salvia, Xuebijing and adjuvant antibiotics for the treatment of cholecystitis

目的探讨在胆囊炎的治疗中应用丹参、血必净辅助抗生素的效果。方法 120例胆囊炎患者,随机分为对照组和试验组,各60例。对照组使用常规西医(抗生素)治疗,试验组使用中西医结合治疗(抗生素+丹参+血必净),比较两组治疗后的C反应蛋白(CRP)、降钙素原(PCT)和肿瘤坏死因子-α(TNF-α)水平变化,并对比两组的治疗效果。结果治疗后,试验组CRP、PCT、TNF-α水平低于对照组,差异具有统计学意义(P<0.05);试验组治疗总有效率为93.33%,高于对照组的80.00%,差异具有统计学意义(P<0.05)。结论在胆囊炎的治疗中将丹参、血必净辅助抗生素治疗可更好的降低炎症因子水平,提高治疗效果。

Objective To investigate the effect of Salvia, Xuebijing and adjuvant antibiotics for the treatment of cholecystitis. Methods 120 patients with cholecystitis were randomly divided into the control group and the experimental group, with 60 cases in each group. The control group was treated with routine Western medicine（antibiotics）, the experimental group was treated with combination of TCM and western medicine（antibiotics plus Salvia plus Xuebijing）. The levels of C-reactive protein（CRP）, procalcitonin（PCT） and tumor necrosis factor-α（TNF-α） and the clinical efficacy between the two groups were compared. Results After treatment, the levels of CRP, PCT and TNF-α in the experimental group were significantly lower than those in the control group（P〈0.05）. The total effective rate of the experimental group was 93.33%, which was significantly higher than 80.00% of the control group, the difference was statistically significant（P〈0.05）. Conclusion In the treatment of cholecystitis, Salvia, Xuebijing and adjuvant antibiotics can better reduce the level of inflammatory cytokines and improve the treatment efficiency.