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阿托伐他汀与辛伐他汀治疗原发性高脂血症的临床药理对照

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摘要 目的探究原发性高脂血症患者接受阿托伐他汀与辛伐他汀治疗的价值。方法 100例原发性高脂血症患者,根据治疗方案不同分为实验组和对照组,各50例。实验组给予阿托伐他汀治疗,对照组给予辛伐他汀治疗。比较两组患者的治疗效果、血脂[高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、甘油三酯(TG)、总胆固醇(TC)]水平、生化指标[肌酸激酶(CK)、丙氨酸氨基转移酶(ALT)、肌酐(Cr)、尿素氮(BUN)]水平以及不良反应发生情况。结果实验组患者治疗总有效率98.00%高于对照组的86.00%,差异具有统计学意义(P<0.05)。两组治疗后的血脂水平、生化指标水平比较,差异无统计学意义(P>0.05)。实验组不良反应发生率为2.00%,对照组不良反应发生率为4.00%,两组比较差异无统计学意义(P>0.05)。结论原发性高脂血症患者接受阿托伐他汀和辛伐他汀治疗,均可取得一定的价值,其中阿托伐他汀的疗效更优。
作者 詹双彬
出处 《中国现代药物应用》 2018年第13期112-114,共3页 Chinese Journal of Modern Drug Application
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