子宫肌瘤切除术中右美托咪定腰硬麻醉的临床镇静效果分析

Clinical Sedation Effect of Dexmedetomidine Lumbar Anesthesia in Myomectomy

目的探讨子宫肌瘤切除术中运用右美托咪定腰硬麻醉的临床镇静效果。方法方便选取该院2016年9月—2017年9月间收治的80例腰硬联合麻醉子宫肌瘤切除术患者,按麻醉用药类型分组:右美托咪定组(n=40,右美托咪定麻醉)、丙泊酚组(n=40,丙泊酚麻醉),分析对比两种麻醉药物的运用效果。结果右美托咪定组患者手术30 min心率(66.8±5.3)次/min、平均动脉压(81.3±6.4)mm Hg较丙泊酚组(71.5±6.3)次/min、(88.5±6.7)mm Hg明显降低(P=0.001、0.000),BIS及Ramsay评分(75.5±7.8)分、(4.0±0.3)分较丙泊酚组(84.3±5.7)分、(2.9±0.2)分更优(P=0.000、0.000),右美托咪定组不良反应发生率12.5%与丙泊酚组15.0%相较差异无统计学意义(P=0.745)。结论子宫肌瘤切除术中运用右美托咪定腰硬麻醉的临床镇静效果显著。

Objective This paper tries to investigate the clinical sedation effect of dexmedetomidine lumbar anesthesia in myomectomy. Methods From September 2016 to September 2017, 80 patients with lumbosacral anesthesia for myomectomy were convenient selected and grouped by type of anesthesia： dexmedetomidine group（n=40, dexmedetomidine anesthesia）;Propofol group（n=40, propofol anesthesia）was used to analyze and compare the effects of the two anesthetic drugs. Results In the dexmedetomidine group, heart rate at 30 minutes was（66.8 ±5.3）times/min and mean arterial blood pressure was（81.3±6.4）mm Hg, decreased significantly than the propofol group of（71.5 ±6.3）times/min and（88.5 ±6.7）mm Hg（P =0.001,0.000）, BIS and Ramsay scores were（75.5±7.8）points and（4.0±0.3）points, better than propofol of（84.3±5.7）points and（2.9±0.2）points（P=0.000, 0.000）. There was no significant difference in the incidence of adverse reactions between 12.5% in the dexmedetomidine group and 15.0% in the propofol group（P=0.745）. Conclusion The clinical sedation effect of dexmedetomidine lumbar anesthesia in uterine fibroid resection was significant.