艾滋病合并马尔尼菲青霉菌病与艾滋病合并非霍奇金淋巴瘤累及腹部淋巴结的鉴别诊断

Differential diagnosis of acquired immune deficiency syndrome patients complicated with penicilliosis marneffei and those complicated with non-Hodgkin lymphoma involving abdominal lymph nodes

目的:探讨艾滋病(AIDS)合并马尔尼菲青霉菌病(PSM)与AIDS合并非霍奇金淋巴瘤(NHL)累及腹部淋巴结影像学特征。方法:回顾性分析经病理诊断及病原学培养确诊的AIDS合并PSM的28例患者及AIDS合并NHL的22例患者的外周血T淋巴细胞计数及腹部淋巴结影像表现。结果:PSM组CD4^+T细胞计数绝对值明显降低、腹腔肿大淋巴结分布范围更广泛、肠系膜分支血管周围分布更多见,NHL组腹腔淋巴结融合趋势更明显。结论:AIDS合并PSM与AIDS合并NHL可通过CD4^+T细胞计数、腹腔淋巴结的分布范围及融合趋势进行鉴别诊断。

Objective：To investigate the differences in epidemiology,clinical and imaging characteristics between acquired immune deficiency syndrome（AIDS）patients complicated with penicilliosis marneffei（PSM）and those complicated with non-Hodgkin lymphoma（NHL）involving abdominal lymph nodes.Methods：The epidemiology,clinical and imaging characteristics of 28 PSM patients and 22 NHL patients with AIDS confirmed by pathological diagnosis and pathogenic culture were retrospectively analyzed.Results：In AIDS patients with PSM,the CD4~＋T cell count was lower,the distribution of abdominal distended lymph nodes was more extensive,and the distribution around mesenteric branches was more common.In AIDS patients with NHL,the trend of abdominal lymph node fusion was more obvious.Conclusions：The epidemiology,clinical and imaging characteristics might be used for the differential diagnosis of AIDS patients complicated with PSM and those complicated with NHL.