肥胖青少年心血管疾病研究进展

Research Progress in Cardiovascular Disease in Obese Adolescents

肥胖青少年是遗传、生活环境、内分泌等因素相互作用导致的一种慢性营养障碍性疾病。青少年肥胖检出率呈现不断上升趋势,已成为血脂异常、高血压、高血糖与胰岛素抵抗重要诱病因素。青少年肥胖不仅影响青少年的身心健康,还与成年期肥胖及慢性疾病的发生密切相关。该文对肥胖青少年心血管疾病现状及与成人心血管疾病发病因素间的关系进行了回顾和总结,指出我国现阶段心血管疾病预防策略研究中存在的问题,并建议开展长期跟踪研究和针对性干预、"体医融合"模式及多学科参与的肥胖青少年循证健康管理研究。

Adolescent obesity is a chronic nutritional disorder caused by interactions of genetics,environment,endocrine and other factors.There is a rising trend in the prevalence of obesity among adolescents.It has become an important inducing factor for dyslipidemia,hypertension,hyperglycemia and insulin resistance.Adolescent obesity affects not only the physical and mental health in adolescents,but also the occurrence of obesity and chronic diseases in adulthood.This article reviews and summarizes the current status of cardiovascular diseases in obese adolescents and their relationships to the factors for cardiovascular disease in adults.Furthermore,this paper points out the existing problems in the study of cardiovascular disease prevention strategies at the present stage in China,and recommends performing the long-term follow-up,targeted intervention,＂integration of body medicine＂and multidisciplinary participation for the evidence-based health management of obese adolescents.