放射性鼻窦炎115例临床分析

Clinical Analysis of 115 Cases of Radioactive Sinusitis

目的探讨放射性鼻窦炎的发生发展规律及相关因素。方法选择该科2016年1月—2017年9月收治的鼻咽癌(NPC)患者171例,均行放射治疗,并在治疗前后对CT扫描、局部体征、临床表现等完整资料进行统计分析。结果 171例鼻咽癌患者,放射治疗前无鼻窦炎体征约20.4%(35/171),放射治疗前鼻窦炎发病率约12.2%(21/171),放射治疗后鼻窦炎发病率约67.2%(115/171)。以放射治疗后6个月发病率最高约44.3%(51/115)。结论放射性鼻窦炎发病率较高,有逐年增长趋势,影响鼻咽癌放射治疗后的预后效果,及早采取中医干预治疗可有效提高鼻咽癌放射治疗患者的生存质量,外科干预治疗可显著提高放射性鼻窦炎的治愈率。

Objective This paper tries to investigate the occurrence and development of radioactive sinusitis and relat- ed factors. Methods 171 cases of nasopharyngeal carcinoma （NPC） patients from January 2016 to September 2017 were all treated with radiotherapy, and CT scans, local signs, and clinical manifestations were analyzed before and after treatment. Results Among 171 patients with nasopharyngeal carcinoma, no sign of sinusitis was 20.4% （35/171） before radiotherapy, 12.2% （21/171） of sinusitis before radiotherapy, and 67.2% of sinusitis after radiotherapy （115/171）. The highest incidence of 6 months after radiotherapy was about 44.3%（51/115）. Conclusion The incidence of radioactive si- nusitis is high, with a year-on-year growth trend, affecting the prognosis of nasopharyngeal carcinoma after radiothera- py. Early intervention in traditional Chinese medicine can effectively improve the quality of life of patients with radio- therapy of nasophryngeal carcinoma. Surgical intervention can significantly improve the radiation sinuses cure rate of inflammation.