空腹血糖和超敏C反应蛋白水平与急性胰腺炎的相关性

Fasting blood glucose and high sensitive C-reactive protein in acute pancreatitis association study

目的探讨血糖及超敏C反应蛋白(hs-CRP)水平与急性胰腺炎预后的相关性。方法随机选择急性胰腺炎患者53例,根据急性胰腺炎的病情分轻度胰腺炎组和中重度胰腺炎组,分别比较空腹血糖及hs-CRP水平,同时观察正常血糖组与高血糖组的住院时间及并发症。结果急性胰腺炎中重度组空腹血糖及hs-CRP水平明显高于轻度组(P<0.05),且住院时间长患者空腹血糖及hs-CRP水平也明显高于住院时间短患者,差异有统计学意义(P<0.05)。结论空腹血糖及hs-CRP水平高低,间接反应急性胰腺炎病情的轻重及并发症情况。早期检测空腹血糖及hs-CRP并控制血糖水平,可能更有利于改善急性胰腺炎的预后。

Objective To observe the changes of the fasting blood glucose and high sensitive C-reactive protein（ hs-CRP） of patients with acute pancreatitis,exploring the fasting blood glucose and the pertinency between the levels of hs-CRP and the prognosis of acute pancreatitis. Methods 53 patients with acute pancreatitis were selected randomly,who were divided into mild pancreatitis group and severe pancreatitis group,to compare the levels of fasting blood glucose and hs-CRP and observe the hospital stay and complications of the normal blood sugar group and the hyperglycemia group at the same time. Results Fasting blood glucose and hs-CRP levelsof paitients with moderate-severe acute pancreatitis were significantly higher than those in mild（ P 〈 0. 05）. The levels of fasting blood glucose and hs-CRP of patients with long hospital stay were significantly higher than those with short hospital stay. The difference was statistically significant（ P 〈 0. 05）. Conclusion Fasting blood glucose and hs-CRP levels indirectly reflect the severity of the disease and complications of acute pancreatitis. Early detection of fasting blood glucose and hs-CRP and control of blood glucose levels may be helpful for the prognosis of acute pancreatitis.