心脏病患者行非心脏手术麻醉恢复期肌松拮抗剂使用安全性评估

Application safety assessment of myocutaneous antagonist in patients with heart disease undergoing non-cardiac surgery during anesthesia recovery

目的:对心脏患者行非心脏手术麻醉恢复期使用肌松拮抗剂的安全性进行探讨。方法:收治行非心脏手术心脏病患者100例,随机分为两组。观察组在手术麻醉恢复期给予肌松拮抗剂治疗,对照组不给予肌松拮抗剂治疗,比较两组麻醉拔管时间、麻醉恢复时间、血压、心率以及不良反应等。结果:观察组麻醉拔管时间、麻醉恢复时间明显短于对照组,差异有统计学意义(P<0.05)。两组麻醉恢复期间血压异常率、心律失常发生率以及再插管发生率、不良反应发生率比较,差异无统计学意义(P>0.05)。结论:心脏病患者行非心脏手术麻醉恢复期使用肌松拮抗剂具有较好的安全性,且能够有效缩短患者麻醉拔管时间。

Objective：To explore the safety of myocutaneous antagonist in patients with heart disease undergoing non-cardiac surgery during anesthesia recovery.Methods：100 cases of patients with heart disease undergoing non-cardiac surgery were divided into two groups randomly.The observation group was treated with myocutaneous antagonist during anesthesia recovery,while the control group did not give myocutaneous antagonist during anesthesia recovery.The time of anesthesia extubation,anesthesia recovery time,blood pressure,heart rate and adverse reactions between groups were compared.Results：The time of anesthesia extubation and anesthesia recovery time were significantly lower in the observation group than in the control group,and the difference was statistically significant（P〈0.05）.There was no statistically significant difference in the abnormality rate of blood pressure,incidence of arrhythmia and incidence of recurrent intubation and incidence of adverse reactions between groups during anesthesia recovery period（P〉0.05）.Conclusion：The application of myocutaneous antagonist in patients with heart disease undergoing non-cardiac surgery during anesthesia recovery was safe and effective,and which could shorten the time of anesthesia extubation effectively.