呼吸道感染患者肺炎支原体和肺炎衣原体检测3385例结果分析

Analysis of the results of mycoplasma pneumoniae and chlamydia pneumoniae in 3385 cases of respiratory infection

目的:检测呼吸道疾病患者血液中肺炎支原体与肺炎衣原体感染情况,分析呼吸道感染病原体分布情况。方法:收治呼吸道感染患者3 385例,分别采用被动凝集法检测肺炎支原体抗体,酶联免疫吸附法检测肺炎衣原体抗体。结果:肺部感染患者与非肺部感染患者相比,均以肺炎支原体阳性感染率最高。两组比较,肺炎支原体阳性率与肺炎衣原体阳性率以及同时感染两者阳性率比较,差异均有统计学意义(P<0.05)。结论:肺炎支原体和肺炎衣原体是呼吸道患者感染的主要病原体之一,尤其在肺部感染包括社区获得性肺炎中检出率较高,其中肺炎支原体感染率高于肺炎衣原体。联合检测有助于临床医生早期鉴别诊断肺部感染,特别是这社区获得性肺炎提供有意义的参考价值。

Objective：To detect the mycoplasma pneumoniae（Mp）and Chlamydia pneumoniae（CP）infection in the blood of patients with respiratory disease,to analyze the distribution of pathogens in respiratory tract infection.Methods：3 385 cases of respiratory tract infection were selected.We detected mycoplasma pneumoniae antibody by passive agglutination and detected chlamydia pneumoniae antibody by enzyme-linked immunosorbent assay.Results：The rate of positive infection of mycoplasma pneumoniae was highest in patients with pulmonary infection and non-pulmonary infections.The positive rate of mycoplasma pneumoniae,the positive rate of chlamydia pneumoniae,and the positive rate of both infections between groups were statistically significant（P〈0.05）.Conclusion：Mycoplasma pneumoniae and chlamydia pneumoniae is one of the main pathogens of respiratory tract infection,especially in lung infection,including community acquired pneumonia（CAP）,and the infection rate of mycoplasma pneumoniae was higher than that of chlamydia pneumoniae.Joint detection helps clinicians to provide a meaningful reference for early differential diagnosis of pulmonary infection,especially for community acquired pneumonia.