新辅助化疗联合保乳手术治疗乳腺癌的临床研究

Clinical research of neoadjuvant chemotherapy combined with breast conserving surgery in the treatment of breast cancer

目的:探讨新辅助化疗联合保乳手术治疗乳腺癌患者的疗效。方法:收治乳腺癌患者80例,随机分为两组。对照组给予常规乳腺癌根治术治疗,观察组给予新辅助化疗联合保乳术治疗,比较两组疗效。结果:观察组术后平均住院时间、术中出血量、手术耗时明显少于对照组,差异有统计学意义(P<0.05)。观察组术后并发症发生率明显低于对照组,差异有统计学意义(P<0.05)。结论:新辅助化疗联合保乳术治疗乳腺癌患者的临床疗效较好,且安全性较高。

Objective：To investigate the clinical effect of neoadjuvant chemotherapy combined with breast conserving surgery in the treatment of breast cancer.Methods：80 cases of patients with breast cancer were divided into two groups randomly.The control group was treated with conventional radical mastectomy,while the observation group was treated with neoadjuvant chemotherapy combined with breast conserving surgery.The clinical effect between groups was compared.Results：The average hospitalization time,intraoperative blood loss and operative time in the observation group were significantly lower than those in the control group,and the difference was statistically significant（P〈0.05）.The incidence of postoperative complications in the observation group was significantly lower than that in the control group,and the difference was statistically significant（P〈0.05）.Conclusion：Neoadjuvant chemotherapy combined with breast conserving surgery was effective and safe in the treatment of breast cancer.