硫酸镁与孟鲁司特联用于小儿支气管哮喘的临床治疗价值

The Clinical Value of Magnesium Sulfate Combined With Montelukast in Children With Bronchial Asthma

目的探讨硫酸镁与孟鲁司特联合治疗小儿支气管哮喘的临床疗效。方法选取支气管哮喘患儿60例,随机分为对照组和观察组各30例。对照组采用硫酸镁单一治疗,观察组采用硫酸镁与孟鲁司特联合治疗;对比分析两组患儿的临床治疗效果。结果分别经临床有效治疗后,观察组总有效率高于对照组,且其FVC、PEFR、FEV1均高于对照组,组间比较差异具有统计学意义(P<0.05);两组不良反应发生率差异无统计学意义(P>0.05)。结论硫酸镁与孟鲁司特两药联用治疗小儿支气管哮喘疗效好、安全性高。

Objective To explore the clinical efficacy of magnesium sulfate combined with montelukast in the treatment of bronchial asthma in children. Methods 60 children with bronchial asthma were selected and randomly divided into control group and observation group, 30 cases in each group. The control group was treated with magnesium sulfate alone, and the observation group was treated with magnesium sulfate and montelukast. The clinical effects of two groups were compared. ResultsAfter effective treatment, the total effective rate of the observation group was significantly higher than that of the control group, and the FVC, PEFR and FEV1 were significantly higher than those in the control group, and the difference between the groups was statistically significant（P〈0.05）; there was no significant difference in the incidence of adverse reactions between the two groups（P〉0.05）. Conclusion The combination of magnesium sulfate and montelukast in the treatment of bronchial asthma in children is effective and safe.