蓝氧联合凯妮汀治疗复发性外阴阴道假丝酵母菌病疗效分析

Efficacy Analysis of Combination of Blue Oxygen and Cimetidine for Recurrent Vulvovaginal Candidiasis

目的探讨对复发性外阴阴道假丝酵母菌病患者联用蓝氧与凯妮汀的效果。方法以110例复发性外阴阴道假丝酵母菌病患者为研究对象,随机分为单药组和联用组,分别给予单纯凯妮汀、蓝氧联合凯妮汀治疗。比较治疗前后外阴瘙痒、白带异味、白带性状评分变化,评估临床有效性并统计复发率。结果治疗后2组外阴瘙痒、白带异味、白带性状评分均较治疗前降低,且联用组评分均低于单药组,治疗前后组内比较和治疗后组间比较差异均有统计学意义(P<0.05);联用组有效性分布及总有效率对比均可见统计学差异(P<0.05),且联用组复发率远低于单药组(P<0.05)。结论对复发性外阴阴道假丝酵母菌病患者联用蓝氧加凯妮汀治疗能够减轻症状,改善疗效,还可显著降低复发率,临床应用价值高,值得推广应用。

Objective To explore the effect of blue oxygen combined with Kennety in the treatment of recurrent vulvovaginal candidiasis. Methods 110 cases of patients with recurrent vulvovaginal candidiasis as subjects were randomly divided into single agent group and combination group,who were respectively treated with Kennety alone,Kennety combined with blue oxygen. The scores of pruritus,leucorrhea unusual？ smell and leucorrhea character before and after treatment were compared,and the effectiveness was evaluated and the recurrence rates were statistically analyzed. Results After treatment,the scores of pruritus,bleucorrhea unusual？ smell and leucorrhea character in the two groups were decreased compared with those before treatment,of which the scores in the combination group were lower than those in the single agent group,and there were significant differences between the 2 groups after treatment and before and after treatment（ P〈0. 05）. There were statistical differences in the effectiveness and total efficiency between the two groups（ P〈0. 05）,and the recurrence rate of the combination group was much lower than that of the single agent group（ P〈0. 05）. Conclusion For patients with recurrent vulvovaginal candidiasis,blue oxygen Fagafaga Kay Bnnie Dean therapy can relieve symptoms,improve curative effect,and significantly reduce the recurrence rate. It has high clinical value and is worthy of popularization and application.