美宝湿润烧伤膏联合电凝术应用于宫颈冷刀锥切术的疗效观察

The efficacy observation of MEIBAO moisturizing cream combined with electrocoagulation applied to cervical cold knife conization

目的探讨美宝湿润烧伤膏联合电凝术在宫颈冷刀锥切术中的应用价值。方法选择2013年1月~2016年6月本院住院行宫颈冷刀锥切患者174例,随机分为观察组(91例)与对照组(83例),两组患者均于经期结束行宫颈冷刀锥切术,观察组宫颈创面采用电凝止血后应用湿润烧伤膏;对照组采用缝合止血。分别记录两组患者手术耗时、术中出血量、术后住院时间、术后并发症情况、术后宫颈创面上皮化情况以及随访HPV-DNA阴性率。结果观察组手术时间、术中出血量、术后并发症总发生率均明显少于对照组,差异有统计学意义(P<0.05);两组住院时间比较,无统计学差异(P>0.05);观察组术后2周及术后1个月宫颈上皮化程度均优于对照组,术后3个月及术后6个月HPV阴性率均高于对照组,差异有统计学意义(P<0.05)。结论美宝湿润烧伤膏联合电凝术应用于宫颈冷刀锥切术,具有操作简便、手术时间短、术中出血少、并发症发生率较低及宫颈愈合效果满意等优点,值得临床推广。

Objective To evaluate the value of MEIBAO moisturizing cream combined with electrocoagulation in the treatment of cervical cold knife conization. Methods From January 2013 to June 2016, 174 patients with cervical cold knife conization in our hospital were random Ly divided into observation group（n=91） and control group（n=83）. The patients in both groups took cervical cold knife conization at the end of the menstrual period, cervical wounds of the observation group took electrocautery hemostatic method and then applying MEIBAO moisturizing cream while control group used suture hemostasis method. Time of surgery, blood loss volume, postoperative hospitalization time,postoperative complications, epithelialization of postoperative wounds and HPV-DNA negative rates after follow-up were recorded. Results The operation time, intraoperative blood loss volume and total postoperative complication rate in the observation group were significantly less than those in the control group（P〈0.05）. There was no significant difference in the length of hospitalization time between the two groups（P〈0.05）. The degree of cervical epithelialization in the observation group at 2 weeks and 1 month after operation was better than that in the control group. The HPV negative rates of the observation group at 3 months and 6 months after operation were significantly higher than those in the control group（P〈0.05）. Conclusion MEIBAO moisturizing cream combined with electrocoagulation is an effective and safe method for cervical cold knife conization. It has the advantages of simple operation, short operative time, less intraoperative bleeding, lower complication rate and satisfactory cervical healing.