左卡尼汀治疗糖尿病合并慢性心力衰竭临床观察

Clinical Observation on Levocarnitine in Treatment of Diabetes Combined with Chronic Heart Failure

目的探讨左卡尼汀治疗糖尿病合并慢性心力衰竭的效果。方法选取2015年10月—2017年10月该科收治的糖尿病合并慢性心衰患者76例,随机分为2组各38例,对照组给予常规治疗,观察组在对照组的基础上给予左卡尼汀,比较疗效。结果观察组总有效率为89.50%,明显优于对照组73.7%(P<0.05);治疗后观察组LVEF(62.03±6.11)%、CO(5.1±0.44)L/min、SV(61.8±8.3)mL、FPG(5.34±0.22)mmol/L等指标明显高于对照组(P<0.05)。结论左卡尼汀可有效提高糖尿病合并慢性心力衰竭的心功能,效果显著,值得应用。

Objective To study the effect of levocarnitine in treatment of diabetes combined with chronic heart failure.Methods 76 cases of patients with diabetes and coronary heart disease in our hospital from October 2015 to October 2017 were selected and randomly divided into two groups with 38 cases in each, the control group used the routine therapy, while the observation group were treated with levocamitine on the basis of the control group, and the curative effect was compared between the two groups. Results The total effective rate in the observation group was obviously better than that in the control group（89.5% vs 73.7%）（P0.05）, and the LVEE, CO, SV and FPG in the observation group after treatment were respectively（62.03±6.11）%,（5.1±0.44）L/min,（61.8±8.3）mL,（5.34±0.22）mmol/L, which were obviously higher than those in the control group（P0.05）. Conclusion The levocarnitine can effectively improve the cardiac function of diabetes combined with chronic heart failure and the effect is obvious, which is worth application.