叶酸辅助治疗对冠心病稳定型心绞痛患者Hcy、脂质代谢、内皮损伤的影响

Effect of Folic Acid Adjuvant Therapy on Hcy and Lipid Metabolism and Endothelial Damage in Patients with Stable Angina Pectoris

分析叶酸辅助治疗对冠心病稳定型心绞痛患者Hcy、脂质代谢、内皮损伤的影响。方法 :取我院收治的冠心病的稳定型心绞痛患者98例,随机将其分成了观察组和对照组,前者实施常规治疗并辅助叶酸治疗,后者单纯使用常规治疗。对比两组患者的血浆Hcy水平、脂质代谢、肉皮功能、黏附分子的变化情况。结果 :比较两组患者的血浆Hcy水平、脂质代谢、肉皮功能、黏附分子的变化情况。观察组患者数据均优于对照组,存在统计学差异(P<0.05)。结论 :冠心病稳定型心绞痛患者辅助叶酸治疗方法,很好地改善了Hcy、脂质代谢、内皮损伤,值得临床推广。

To analyze the effect of folic acid adjuvant therapy on Hcy and lipid metabolism and endothelial damage in patients with stable angina pectoris.Methods ：98 patients with stable angina pectoris treated in our hospital were randomly divided into the observation group and the control group.The former was treated with routine treatment and assisted with folic acid treatment,and the latter was treated with conventional treatment.The plasma Hcy level,lipid metabolism,skin function and adhesion molecules of the two groups were compared.Results ：the plasma Hcy level,lipid metabolism,skin function and adhesion molecules of the two groups were compared.The data of the observation group were better than those of the control group,and there was statistical difference（P〈0.05）.Conclusion ：folic acid therapy in patients with stable angina pectoris of coronary heart disease can improve Hcy,lipid metabolism and endothelial injury,which is worthy of clinical promotion.