针刺配合常规降眼压药对原发性开角型青光眼眼压的影响

Effect of Acupuncture plus Conventional Ocular Hypotensive Agents on Intraocular Pressure in Primary Open-angle Glaucoma

目的观察针刺配合常规降眼压药对原发性开角型青光眼患者眼压的影响。方法 58例眼压控制稳定的原发性开角型青光眼患者,随机分为对照组30例和治疗组28例。对照组继续使用原有的降眼压药拉坦前列腺素滴眼液控制眼压,治疗组在对照组的基础上配合针刺治疗。观察两组治疗后8:00AM、12:00AM、2:00PM、6:00PM时的眼压及治疗前后视力变化,并比较两组临床疗效。结果治疗组治疗后8:00AM、12:00AM、2:00PM、6:00PM时眼压,较对照组均有不同程度降低,差异具有统计学意义(P<0.05)。治疗组24 h眼压波动幅度较对照组减小,两组间差异具有统计学意义(P<0.05)。对照组治疗前后视力无明显变化,差异无统计学意义(P>0.05);治疗组治疗后视力较治疗前改善,差异有统计学意义(P<0.05)。治疗组的总有效率为89.3%,对照组为10.0%,两组比较差异有统计学意义(P<0.01)。结论针刺可使青光眼患者的24 h眼压波动幅度减小,并且对青光眼患者的视力有较好的临床疗效。

Objective To observe the effect of acupuncture plus conventional ocular hypotensive agents on intraocular pressure of patients with primary open-angle glaucoma（POAG）. Method Fifty-eight POAG patients with stable intraocular pressure control were randomized into a control group of 30 cases and a treatment group of 28 cases. The control group continued to use the original ocular hypotensive agent latanoprost eye drops to control the intraocular pressure, while the treatment group was additionally given acupuncture treatment. The intraocular pressure was measured at 8：00 AM, 12：00 AM, 2：00 PM and 6：00 PM after the treatment, and the changes in vision after the treatment were observed, and the clinical efficacies were compared between the two groups. Result The treatment group was lower than the control group in comparing the intraocular pressure at 8：00 AM, 12：00 AM, 2：00 PM and 6：00 PM after the treatment, and the differences were statistically significant（P〈0.05）. The 24-hour intraocular pressure fluctuation range in the treatment group was significantly smaller than that in the control group（P〈0.05）. The vision did not show significant change in the control group after the intervention（P〈0.05）; the vision was significantly improved after the intervention in the treatment group（P〈0.05）. The total effective rate was 89.3% in the treatment group versus 10.0% in the control group, and the between-group difference was significant（P〈0.01）. Conclusion Acupuncture can reduce the 24-hour intraocular pressure fluctuation range in glaucoma patients, and can produce a satisfactory efficacy in improving the vision.