HC2 HPV联合TCT检测在宫颈癌早期筛查中的临床效果

Clinical effect of HC2 HPV combined with TCT detection in early screening of cervical cancer

目的:探讨在宫颈癌早期筛查中应用HC2 HPV联合TCT检查的临床价值。方法:收治宫颈病理学检查异常患者240例,分为甲组、乙组与丙组。甲组接受HC2 HPV检测,乙组接受TCT检测,丙组接受HC2 HPV联合TCT检测,比较3组检测结果。结果:甲组、乙组和丙组检测数据差异有统计学意义(P<0.05);甲组CINⅠ型、CINⅡ型及CINⅢ型间真阳性率差异有统计学意义(P<0.05);乙组CINⅢ型和CINⅡ型间真阳性率差异有统计学意义(P<0.05),CINⅡ型和CINⅠ型间真阳性率差异无统计学意义(P>0.05);宫颈癌与CINⅢ型间真阳性率差异有统计学意义(P<0.05)。结论:在宫颈癌早期筛查中应用HC2 HPV联合TCT检测与单一使用HPV和TCT检测可更便捷地进行早期筛查,为临床预防提供重要指导依据。

Objective：To explore the clinical value of HC2 HPV combined with TCT detection in early screening of cervical cancer.Methods：240 cases of patients with abnormal cervical pathological examination were selected.They were divided into the A group,the B group and the C group.The A group received HC2 HPV detection;the B group received TCT detection;the C group received HC2 HPV combined with TCT detection.We compared the results of the three groups.Results：The difference of the test data between the 3 groups was statistically significant（P〈0.05）.In the A group,the true positive rate of CIN Ⅰ,CIN Ⅱ and CIN Ⅲwas statistically significant（P〈0.05）.In the B group,the true positive rate of CIN Ⅲ and CIN Ⅱ was statistically significant（P〈0.05）,and there was no significant difference in the true positive rate between CIN Ⅱ and CIN Ⅰ（P〈0.05）.The true positive rate of cervical cancer and CIN Ⅲ was statistically significant（P〈0.05）.Conclusion：In the early screening of cervical cancer,compared with the single use of HPV and TCT,the application of HC2 HPV combined with TCT detection can be more convenient for early screening,and it can provide important guidance for clinical prevention.