保留胸前神经和肋间臂神经的改良式乳腺癌根治术的应用安全性与有效性

Safety and Efficacy of Modified Radical Mastectomy Remain Chest Nerve and Intercostobrachial Nerve for the Breast Cancer

目的探讨保留胸前神经和肋间臂神经的改良式乳腺癌根治术的应用安全性与有效性。方法选择女性乳腺癌患者246例,根据随机信封抽签原则分为观察组与对照组,各123例。对照组给予乳腺癌标准根治术,观察组给予保留胸前神经和肋间臂神经的改良式乳腺癌根治术,记录2组有效性与安全性。结果观察组术后引流时间、引流量及术中出血量均低于对照组(P<0.05)。观察组术后1个月皮瓣下积液、皮瓣坏死、感染、上肢淋巴水肿等发生率明显低于对照组(P<0.05)。术后6个月,观察组的生存质量优于对照组(P<0.05);2组复发率及远处转移率对比,差异无统计学意义(P>0.05)。结论保留胸前神经和肋间臂神经的改良式乳腺癌根治术的应用有更好的微创性,能促进患者的康复,减少术后并发症的发生,提高患者生存质量,但是需要在临床上减少复发的发生。

Objective To explore the safety and efficacy of modified radical mastectomy remain chest nerve and intercostobrachial nerve for breast cancer. Methods 246 breast cancer patients were divided into the observation group and the control group,with 123 patients in each group,the control group was given radical resection,the observation group was given modified radical mastectomy remain chest nerve and intercostobrachial nerve,effectiveness and safety of the 2 groups were recorded. Results All patients completed the operation,the drainage time,total lead flow,the amount of bleeding in the observation group were significantly less than those of the control group （ P 〈0.05）.The incidence of effusion,flap necrosis,infection,upper limb lymph edema in the observation group 1 month after surgery was significantly lower than the control group （ P 〈0.05）.After 6 months of treatment,quality of life in the observation group was superior to the control group（ P 〈0.05）.The local recurrence rates and distant metastasis rates of the 2 groups had no statistical difference（ P 〉0.05）. Conclusion The application of modified radical mastectomy remain chest nerve and intercostobrachial nerve for breast cancer is minimally invasive,it can promote the rehabilitation of patients,reduce the incidence of postoperative complications,improve the quality of survival,but need to reduce recurrence in clinical.